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Genome analysis of 17 extensively drug-resistant strains reveals new potential mutations for resistance

Genome Announcements (2014) 2(4)
DOI: 10.1128/genomeA.00759-14
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Abstract

We report the whole-genome sequence of an extensively drug-resistant (XDR) tuberculosis (TB) strain of Latin American-Mediterranean (LAM) lineage. This strain is phenotypically resistant to aminoglycosides, but carries no related mutations in rrs, tlyA, and eis. Through genome analysis comparison with 16 XDR strains, we found 218 non-synonymous single nucleotide polymorphisms (SNPs) shared that could confer resistance.

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APA

Guio, H., Tarazona, D., Galarza, M., Borda, V., & Curitomay, R. (2014). Genome analysis of 17 extensively drug-resistant strains reveals new potential mutations for resistance. Genome Announcements, 2(4). https://doi.org/10.1128/genomeA.00759-14

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