Membrane traffic: The exocyst meets the cell cycle

Abstract

A new study describes a novel regulatory event that results in the inhibition of exocytic transport of a specific class of Golgi-derived vesicles during mitosis. The mechanism of inhibition is shown to involve direct phosphorylation of a subunit of the exocyst by a specific cyclin-dependent kinase complex. © 2013 Elsevier Ltd. All rights reserved.