Many aspects of brain development, function, and repair depend on the interaction of neurons with brain immune cells, the microglia. By combining CLEM and SPIM microscopy, a recent study has challenged the current view that microglia can “eat” entire synapses, highlighting the incredible complexity of neuronal-microglial interactions in vivo.
Villani, A., & Peri, F. (2019, January 7). Microglia: Picky Brain Eaters. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2018.12.013