How do cells stop transcribing RNA Polymerase II to promote proper gene expression and prevent transcriptional havoc in the genome? In the case of Leishmania, a uniquely modified DNA base blocks RNA Polymerase II and suggests an interesting new model for transcription termination. © 2012 Elsevier Ltd.
Hazelbaker, D. Z., & Buratowski, S. (2012, November 20). Transcription: Base J blocks the way. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2012.10.010