Cadherins and catenins evidently partnered at the dawn of the animal kingdom to enable the first polarized epithelium, and perhaps animal evolution itself. New evidence from a primitive slime mold, however, suggests that α- and β-catenins may have engaged this function independently, long before cadherins arrived on the scene. © 2011 Elsevier Ltd All rights reserved.
Reynolds, A. B. (2011, June 7). Epithelial organization: New perspective on α-catenin from an ancient source. Current Biology. Cell Press. https://doi.org/10.1016/j.cub.2011.04.043