PD16-03 A PROSPECTIVE STUDY OF SILODOSIN IN COMPARISION WITH TAMSULOSIN IN THE MANAGEMENT OF PATIENTS IN ACUTE URINARY RETENTION DUE TO BENIGN HYPERPLASIA OF PROSTATE.

Abstract

INTRODUCTION AND OBJECTIVES: Some articles reported that PSA were reduced by approximately 50% after several months of treatment. However£a study from Korea found that PSA decreased by only about 36% after 1-year finasteride taking. The aim of our study was to evaluate the effect of finasteride on PSA in Chinese population. METHODS: From Feb 2011 to Jan 2012, 83 BPH patients were enrolled in our study. All the patients were older than 50 years old and all of them received combined therapy (finasterideþdoxazosin). If PSA was greater than 4 ng/ml, a prostate biopsy is required to confirm whether it was benign or not. The patients with age less than 50, other drugs therapy, AUR history, prostate cancer, diabetes, acute prostatitis, history of baldder or prostate surgery were excluded from the study. All the patients were required for 1-year follow-up. PSA level and TPV was measured at the start, 6 months and 12 months, respectively. RESULTS: 79 patients completed the follow up. The mean baseline PSA, PSA at 6 months and PSA at 12 months was 3.40ng/ ml,