Seizures are believed to be a dose-dependent side effect of clozapine. In this case report, we describe a patient who had tonic-clonic seizures after using a low dose clozapine who did not have any seizure risk. The 29-year-old male patient had been followed-up with a diagnosis of schizophrenia for about 5 years. When using clozapine 200 mg/day he had a tonic-clonic seizure with bilateral diffuse epileptic activity in electroencephalography (EEG). In the literature, there are a few case reports about low-dose clozapine-induced seizure. Seizures were observed in our case with a low dose of clozapine (200 mg/day) making this case remarkable. EEG monitoring at regular intervals and examination of plasma levels of clozapine could be useful in preventing the development of seizures.
CITATION STYLE
Bolu, A., Akarsu, S., Pan, E., Aydemir, E., & Oznur, T. (2017). Low-dose clozapine-induced seizure: A case report. Clinical Psychopharmacology and Neuroscience, 15(2), 190–193. https://doi.org/10.9758/cpn.2017.15.2.190
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