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Characterization of FOX-3, an AmpC-type plasmid-mediated β-lactamase from an italian isolate of Klebsiella oxytoca

Antimicrobial Agents and Chemotherapy (1998) 42(2) 464-467
DOI: 10.1128/aac.42.2.464
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Abstract

Klebsiella oxytoca 1731, which showed a wide spectrum of resistance to β-lactams, including cefoxitin, was isolated in 1994 from a patient in Genoa, Italy. This strain contained a plasmid-mediated AmpC β-lactamase with a pI of 7.25. Sequencing of the corresponding DNA of K. oxytoca 1731 revealed 96 and 97% identities of the deduced amino acid sequence with FOX-1 and FOX- 2, respectively.

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Marchese, A., Arlet, G., Schito, G. C., Lagrange, P. H., & Philippon, A. (1998). Characterization of FOX-3, an AmpC-type plasmid-mediated β-lactamase from an italian isolate of Klebsiella oxytoca. Antimicrobial Agents and Chemotherapy, 42(2), 464–467. https://doi.org/10.1128/aac.42.2.464

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