Foxp3+ regulatory T cells can manifest functional " reprogramming" during inflammation. In this issue of Immunity, Sharma et al. (2010) show how reprogramming is beneficial to CD8+ T cell immunity and how the tumor microenvironment inhibits this process. © 2010 Elsevier Inc.
Piccirillo, C. A. (2010, December 14). Treg’s Alter Ego: An Accessory in Tumor Killing. Immunity. Cell Press. https://doi.org/10.1016/j.immuni.2010.12.005