Neuroimaging in posterior cortical atrophy: an integrative review for clinicians and radiologists

Abstract

Posterior cortical atrophy (PCA) is most frequently an atypical variant of Alzheimer’s disease that primarily manifests through visual symptoms of cortical origin. This review provides a comprehensive overview of neuroimaging in PCA, addressing key anatomical and clinical aspects as well as characteristic findings across different imaging modalities. It is intended for non-radiologist clinicians and radiologists who may encounter cognitive dysfunction less frequently, aiming to enhance early recognition and accurate interpretation of imaging studies.