Patho-Epigenetics

Abstract

Patho-epigenetics is a new discipline dealing with the description of pathologic changes elicited by epigenetic dysregulation. Patho-epigenetic processes contribute to the development of both rare syndromes and diseases of high prevalence in human populations. In this short review, we summarize the basic epigenetic regulatory mechanisms in a nutshell and briefly outline how epigenetic reprogramming contributes to all forms of tumorigenesis and plays a role both in the initiation and progression of neoplasms.