Noninvasive LV pressure estimation using subharmonic emissions from microbubbles

Citations of this article
Mendeley users who have this article in their library.


To develop a new noninvasive approach to quantify left ventricular (LV) pressures using subharmonic emissions from microbubbles, an ultrasound scanner was used in pulse inversion grayscale mode; unprocessed radiofrequency data were obtained with pulsed wave Doppler from the aorta and/or LV during Sonazoid infusion. Subharmonic data (in dB) were extracted and processed. Calibration factor (mm Hg/dB) from the aortic pressure was used to estimate LV pressures. Errors ranged from 0.19 to 2.50 mm Hg when estimating pressures using the aortic calibration factor, and were higher (0.64 to 8.98 mm Hg) using a mean aortic calibration factor. Subharmonic emissions from ultrasound contrast agents have the potential to noninvasively monitor LV pressures. © 2012 American College of Cardiology Foundation.




Dave, J. K., Halldorsdottir, V. G., Eisenbrey, J. R., Raichlen, J. S., Liu, J. B., McDonald, M. E., … Forsberg, F. (2012, January). Noninvasive LV pressure estimation using subharmonic emissions from microbubbles. JACC: Cardiovascular Imaging.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free