Correlation between iron deficiency anemia and HbA1C levels in type 2 diabetes mellitus

Abstract

The HbA1c levels, in general reflects the diabetic patients Glycaemic control status over the previous 3 months. HbA concentrations may be increased by Anaemia due to iron deficiency, independent of glycaemia in diabetic patients. Henceforth this study serves to find if there is a positive correlation between the iron deficiency anaemia status & the HbA1c levels amidst the diabetic population. Cases-100 iron-deficiency anaemia patients with diabetes having controlled plasma glucose levels, Controls -100 non-anaemic diabetic individuals. The study was done in the premises of Sree Balaji Medical College & Hospital. HbA levels was measured by ion exchange chromatography, ferritin by particle enhanced turbidometric immunoassay method, fasting plasma glucose by GOD - POD method.We found that HbA1c was elevated (7.3±0.9) in iron-deficient diabetic individuals compared to normal level (5.4±0.6) in controls. The study showed that there was a positive correlation between the iron deficiency anaemia status and increased HbA levels in the controlled diabetic population. Hence forth, the clinical significance of evaluating the iron deficiency anaemia status in diabetic patients has been proved to be significant in planning their further course of prompt diabetic management.