A hairy tale: SIRT 7 safeguards skin stem cells during aging

  • Simon M
  • Emmrich S
  • Seluanov A
  • et al.
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Abstract

Stem cell regulation during both normal development and aging has become one of the fastest growing topics in biology. Here, new work by Li et al (2020) offers insight into the aging process within epithelial skin stem cells and highlights how SIRT7, a member of the sirtuin family of protein deacylases and mono-ADP ribosylases, protects adult hair follicle stem cells from aging by ensuring their hair cycle progression.

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Simon, M., Emmrich, S., Seluanov, A., & Gorbunova, V. (2020). A hairy tale: SIRT 7 safeguards skin stem cells during aging. The EMBO Journal, 39(18). https://doi.org/10.15252/embj.2020106294

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