Using Moringa oleifera stem extract for green synthesis, characterization, and anti-inflammatory activity of silver oxide nanoparticles

Abstract

Recently, nanoparticles from 1 to 100 nm gained attention. Due to their eco-friendliness and medicinal potential, natural ingredients are used more to synthesise AgONPs. This work synthesises AgONPs from Moringa oleifera stem extract and tests their anti-inflammatory activity. Prepared AgONPs were characterised through UV-Visible, FTIR, XRD, SEM and EDX. According to the results, Moringa oleifera stem extract reduced silver ions to AgO with an average crystalline size of 23 nanometres. In addition, the study compared the anti-inflammatory properties of green AgONPs with those of standard pharmacological drugs. At a dose of 80 mL-1, synthesised nanoparticles showed strong anti-inflammatory effects compared to the drug diclofenac sodium, which had an 85% inhibition rate. The AgONPs only had a 78% inhibition rate. Based on the results, AgONPs are compatible with diclofenac sodium. These findings show that AgONPs synthesised from Moringa oleifera stem extract may cure inflammation related diseases.