Interaction of bifidobacterial lipoteichoic acid with human intestinal epithelial cells

Abstract

Binding of the lipoteichoic acids of Bifidobacterium bifidum to human colonic epithelial cells appeared to be specific, reversible, and cell concentration and time dependent. A single population of approximately 8.3 x 108 binding sites per cell was detected, with a dissociation constant of 125 μM. Ester-linked fatty acids are essential for binding.