Lupus aortitis successfully treated with moderate-dose glucocorticoids: A case report and review of the literature

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Abstract

Lupus aortitis is a rare and potentially life-Threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of systemic lupus erythematosus who was diagnosed with aortitis. Her symptoms and laboratory and imaging abnormalities rapidly resolved upon the administration of moderate-dose glucocorticoids. We subsequently performed a literature review of similar cases to identify the appropriate treatment and discuss these cases. A study of further cases will be needed to identify the characteristics of patients who would benefit from moderate-dose glucocorticoid therapy.

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Akebo, H., Sada, R., Matsushita, S., Ishimaru, H., Minoda, S., Miyake, H., … Hatta, K. (2020). Lupus aortitis successfully treated with moderate-dose glucocorticoids: A case report and review of the literature. Internal Medicine, 59(21), 2789–2795. https://doi.org/10.2169/internalmedicine.4964-20

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