Parkinson's disease (PD) is a common, progressive and multisystem neurodegenerative disorder characterized by motor and non-motor symptoms. Advanced magnetic resonance imaging, positron emission tomography, and functional magnetic resonance imaging can render the view toward understanding the neural basis of these non-motor syndromes, as they help to understand the underlying pathophysiological abnormalities. This review provides an up-to-date description of structural and functional brain alterations in patients with PD with cognitive deficits, visual hallucinations, fatigue, impulsive behavior disorders, sleep disorders, and pain.
Prell, T. (2018, March 12). Structural and functional brain patterns of non-motor syndromes in Parkinson’s disease. Frontiers in Neurology. Frontiers Media S.A. https://doi.org/10.3389/fneur.2018.00138