Lewis base-catalyzed diastereoselective [3 + 2] cycloaddition reaction of nitrones with electron-deficient alkenes: An access to isoxazolidine derivatives

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Abstract

A Lewis base-catalyzed [3 + 2] cycloaddition reaction of nitrones with electron-deficient alkenes has been achieved under mild reaction conditions, affording various functionalized isoxazolidine derivatives as single diastereomers in moderate to excellent yields.

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Liu, H., Zhao, Y., Li, Z., Jia, H., Zhang, C., Xiao, Y., & Guo, H. (2017). Lewis base-catalyzed diastereoselective [3 + 2] cycloaddition reaction of nitrones with electron-deficient alkenes: An access to isoxazolidine derivatives. RSC Advances, 7(47), 29515–29519. https://doi.org/10.1039/c7ra04264g

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