We report a rare case of atheromatous plaque formation in the offending parent artery of a 39-year-old man 11 months after Gamma Knife stereotactic radiosurgery (GKSR) for trigeminal neuralgia (TN). Focal atheromatous changes to the parent vessel remote from the root entry zone (REZ) of the trigeminal nerve were discovered during rescue open surgery; this has seldom been reported. Our report suggests that younger male TN patients with hyperlipidemia who receive GKSR may have an increased risk of post-radiation atheromatous formation. A review of the literature is carried out together with a discussion of the possible mechanism by which this complication occurred.
Li, C. S., Liu, J. T., Chang, C. S., & Liao, W. J. (2015). Atheromatous plaque formation in a man with high-risk atherosclerosis after Gamma Knife stereotactic radiosurgery for trigeminal neuralgia. Tzu Chi Medical Journal, 27(4), 181–183. https://doi.org/10.1016/j.tcmj.2014.06.002