PHP133 PERSONALIZED PHARMACOTHERAPY AND ANALYSIS OF EXTEMPORANEOUS DOSAGE FORMS FOR CHILDREN IN UKRAINE

  • Maynych Y
  • Zalis'ka O
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Abstract

OBJECTIVES: Pharmacotherapy of children requires the use of drugs for individual preparation of personalized treatment. Medications extemporal manufacturing approach allows for Personalized Medicine. The use of extemporaneous preparations to precisely match the appropriate concentration of drug forms, volume and available dosage forms for komplayensu, extemporaneous medicines do not contain stabilizers, preservatives, it is important for children with allergic diseases. METHODS: The ABC-analysis was conducted of 3525 prescription extemporaneous preparations which were made in 8 pharmacies specialized of Western Ukraine regions for 2007- 2009. RESULTS: The total list of pediatric formulations consisted of 106 items. Determined that the practical range of medicines includes 7 extemporaneous dosage forms, including solutions of 45% solutions, ointments 23% and 12% suspensions et al. Revealed that the production of extemporaneous preparations seasonal infl uences. Increasing production of liquids, powders at the time of respiratory exacerbation in children. Distinguished set of extemporaneous preparations, which are often assigned practical pediatrician in Ukraine: protargol drops-when rhinitis, cough mixture, powder eufi linu with glucose-with bronchitis, Foenuculi water-with fl atulence, pepsin solution with hydrochloric acid-in violation of appetite, anestezynum suspension; dexamethasone ointment, betamethasone ointment-for allergies vitamin powder. Determined extemporaneous medicines for children, which have no analogues in industrial production-a solution of pepsin with hydrochloric acid, dexamethasone ointment, paste Lassara with oil Plum; diazolinum powder with calcium gluconate and glucose-from allergies, suppositories with cocoa butter and levomitsetinum- with diarrhea, Foenuculi water-with fl atulence in newborns and infants. CONCLUSIONS: Using drugs extemporal medicines, namely those that have no industrial counterparts, to ensure individualized pharmacotherapy children pick up the dose, volume of product, and prevent undesirable side reactions, especially for treatment of chronic diseases in children with allergic manifestations and provide a personalized therapy in pediatric practice

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APA

Maynych, Y., & Zalis’ka, O. (2010). PHP133 PERSONALIZED PHARMACOTHERAPY AND ANALYSIS OF EXTEMPORANEOUS DOSAGE FORMS FOR CHILDREN IN UKRAINE. Value in Health, 13(7), A429. https://doi.org/10.1016/s1098-3015(11)72797-8

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