Chiral ion mediated asymmetric chemistry

Abstract

The octahedral geometry of pentavalent hexacoordinated phosphorus allows the formation of chiral anions by complexation of the central phosphorus atom with three bidentate ligands. These simple-to-make derivatives can be combined with chiral cations and often display efficient NMR chiral shift, resolving and asymmetry-inducing properties. This paper is a short review of our research efforts directed towards the development of chiral anion mediated asymmetric chemistry.