Synthesis of 5-(alkylphenylphosphoryl)-5-methyl-3,4-dihydro-2H-pyrroline N-oxide as a new spin trapping reagent

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Abstract

Novel DMPO analogues attached to a phenyl group at the phosphorus atom were synthesized and examined for their ability in the spin trapping of oxygen-centered radicals. The lipophilicities of these analogues were higher than those of DMPO.

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Shioji, K., Tsukimoto, S., Tanaka, H., & Okuma, K. (2003). Synthesis of 5-(alkylphenylphosphoryl)-5-methyl-3,4-dihydro-2H-pyrroline N-oxide as a new spin trapping reagent. Chemistry Letters, 32(7), 604–605. https://doi.org/10.1246/cl.2003.604

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