Therapeutic Management of Leptospirosis in a Two Dogs: A Case Report

Abstract

This report deals with the successful clinical management of Leptospirosis infection in two dogs. Two dogs one Pomeranian and one Labrador of ages two years and four years respectively was presented to the Referral Veterinary Polyclinic, IVRI Izatnagar in recumbent stage having history of acute onset of vomiting, anorexia, polydipsia, polyuria and weight loss, coughing, lethargy. There were no proper record of deworming and vaccination. Clinical examination revealed icteric conjunctival, gingival and penile mucous membrane, fever, depressed mentation, enlarged lymph node, tachycardia and tachypnea and slightly distended abdomen, Abdominal palpation and ultrasonographic examination revealed hepato-renal abnormality and Superficial lymph nodes (popliteal, and submandibular) were greatly enlarged. The hemato-biochemical report showed a marked reduction in Hb, TEC, PCV, hypoalbuminemia and elevated SGPT, SGOT, BUN, Creatinine and ALP level. Blood smear examination was negative for hemoprotozoan infection. Serum sample of the dogs was positive for Ab titre during MAT. Based on clinical signs and laboratory findings the case was diagnosed as Leptospirosis in dogs having hepato-renal complications. Following the diagnosis of the case, treatment was started with Amoxicillin-clavulanate for 15 days followed by doxycycline next 15 days along with supportive treatment. Both animals start recovering from 15th day onward. Both animals recovered uneventfully after treatment. Introduction