Mm 46115, a new antiviral antibiotic from actinomadura pelletieri. Characteristics of the producing cultures, fermentation, isolation, physico-chemical and biological properties

Abstract

Six strains of Actinomadura pelletieri were shown to produce a novel macrolide antibiotic, designated MM 46115. MM 46115 was active against parainfluenza virus 1 and 2 and Grampositive bacteria. Methods are described for the production of MM 46115 by strain IP 729.63, and for the isolation of the compound from a butanol extract of the culture filtrate. © 1990, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.