Ribosome-protected fragments from two of the large-sized reovirus mRNAs were recovered from sparsomycin-blocked 80S initiation complexes. The sequence of each protected oligonucleotide was determined. The ribosome binding site of each message includes the m7G cap and a centrally positioned AUG codon. An adenine residue occurs three nucleotides upstream from the initiator codon, thus conforming to the pattern [AG]NNAUG observed for nearly all eucaryotic initiation sites.
CITATION STYLE
Kozak, M. (1982). Sequences of ribosome binding sites from the large size class of reovirus mRNA. Journal of Virology, 42(2), 467–473. https://doi.org/10.1128/jvi.42.2.467-473.1982
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