Dimensions that interfere with adherence to medication in substance-related disorders: Integrative review

Abstract

Objective: To analyze the scientific production about the dimensions that interfere in the adherence to pharmacological therapy of individuals with mental disorders related to substance abuse from 2006 to April 2017. Method: Integrative literature review of publications indexed in the following three databases LILACS, CINAHL and PUBMED, performed in April 2017. Results: The 43 studies that met the eligibility criteria were analyzed. Such analysis made it possible to identify factors that have positive or negative impact on adherence to pharmacological therapy, grouped according to the five dimensions that determine the adherence proposed by the World Health Organization, namely: socioeconomic, health team/system, disease, treatment, and individual/patient. Conclusion: Although pharmacological therapy is crucial in the management of individuals with substance-related disorders, implementing the treatment is challenging because of the different interactive dimensions that directly impact the process of treatment adherence.