The recognition of multiple ligands at a single molecular surface is essential to many biological processes. Conformational flexibility has emerged as a compelling strategy for association at such convergent binding sites. Studies over the past few years have brought about a greater understanding of the role that protein plasticity might play in protein- protein interactions.
Sundberg, E. J., & Mariuzza, R. A. (2000, July 1). Luxury accomodation: The expanding role of structural plasticity in protein-protein interaction. Structure. Current Biology Ltd. https://doi.org/10.1016/S0969-2126(00)00167-2