The response of fibroblast cells to periodically poled LiTaO3 ferroelectric crystals has been studied. While fibroblast cells do not show morphological differences on the two polarization directions, they show a tendency to avoid the field gradients that occur between polarization domains of the ferroelectric. The response to the field gradients is fully established after one hour, a time at which fibroblasts form their first focal contacts. If suspension cells, with a lower tendency to establish strong surface contacts are used, no influence of the field gradients is observed. © 2013 Christophis et al.
Christophi, C., Cavalcanti-Adam, E. A., Hanke, M., Kitamura, K., Gruverman, A., Grunze, M., … Rosenhahn, A. (2013). Adherent cells avoid polarization gradients on periodically poled LiTaO3 ferroelectrics. Biointerphases, 8(1), 1–9. https://doi.org/10.1186/1559-4106-8-27