The blood pressure and daily urinary catecholamine excretion were examined in nineteen non-smoking post-menopausal women, receiving estrogen replacement therapy for a period of 4 months. The estrogens administered consisted of 17β-estradiol combined with estriol and norethisterone acetate administered sequentially (Trisequens R, Novo, Denmark). Before the institution of treatment, the blood pressure and urinary catecholamine excretion were normal. After a period of 4 months, no change in blood pressure was observed. However, a marked and significant increase in daily urinary catecholamine excretion was noticed (72.3 ± 18.96 μg/day to 102.0 ± 26.0 μg: p < 0.01). The pathogenetic implications of this increase are discussed. © 1986.
Blum, M., Assa, S., Bacalu, B., Honig, B., & Blum, I. (1986). The influence of short-term estrogen replacement therapy (ERT) on the blood pressure and daily urinary catecholamine excretion in a small group of post-menopausal women. European Journal of Obstetrics and Gynecology and Reproductive Biology, 23(3–4), 195–199. https://doi.org/10.1016/0028-2243(86)90148-6