Calcium binding properties of rabbit liver protein disulfide isomerase

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Abstract

We have characterized the Ca2+ binding properties of protein disulfide isomerase (PDI). It binds 19 mol Ca2+/mol protein with low affinity, which is reduced by increasing the ionic strength. Ca2+ induced conformational changes detected by UV difference spectroscopy. These Ca2+ binding properties resemble those of a sea urchin egg 58 kDa protein.© 1994 Academic Press, Inc.

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Lebeche, D., Lucero, H. A., & Kaminer, B. (1994). Calcium binding properties of rabbit liver protein disulfide isomerase. Biochemical and Biophysical Research Communications, 202(1), 556–561. https://doi.org/10.1006/bbrc.1994.1964

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