Doença de Crohn vulvoperineal responsiva ao metronidazole

Abstract

Crohńs disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological lesions are the inaugural event and may constitute the only sign of the disease. Vulvoperineal involvement is rare, may precede bowel symptoms by months to years and may go unrecognized. Due to the paucity of reports of Crohńs disease at this location and in the absence of randomized trials, there are no standard treatments for the cutaneous disease. We describe the case of a 47 year-old woman with vulvope-rineal Crohńs disease without digestive involvement, that was successfully managed with metronidazole. © 2013 by Anais Brasileiros de Dermatologia.