Objective: To report a case of a heterotopic primary abdominal pregnancy after two-blastocyst IVF-ET. Design: Case report. Setting: University-based IVF program. Patient(s): A woman with a heterotopic abdominal pregnancy after IVF-ET. Intervention(s): Pituitary down-regulation with luteal antagon, ovulation induction with menotropins, IVF-ET, progesterone in oil for luteal support, dilation and curettage for missed abortion, laparoscopy, and resection of abdominal gestation. Main Outcome Measure(s): Human chorionic gonadotropin levels, pelvic ultrasound examinations, and laparoscopic and pathologic findings. Result(s): A heterotopic abdominal pregnancy occurred after a two-blastocyst IVF-ET. The concurrent intrauterine gestation resulted in a miscarriage. Conclusion(s): The number of embryos transferred has been identified as a powerful risk factor for heterotopic pregnancy; however, heterotopic pregnancy can occur following a two-embryo, blastocyst stage transfer. © 2007 American Society for Reproductive Medicine.
Knopman, J. M., Talebian, S., Keegan, D. A., & Grifo, J. A. (2007). Heterotopic abdominal pregnancy following two-blastocyst embryo transfer. Fertility and Sterility, 88(5), 1437.e13-1437.e15. https://doi.org/10.1016/j.fertnstert.2006.12.083