Rising antibiotic resistance means that alternative antibacterial strategies are sorely needed. In this issue, Zhu et al. (2015) report the use of a Caenorhabditis elegans model to validate the Pseudomonas aeruginosa virulence factor LasB as a potential therapeutic target and to identify a LasB inhibitor with in vivo efficacy.
Melander, R. J., & Melander, C. (2015, April 23). From worms to targeting virulence factors. Chemistry and Biology. Elsevier Ltd. https://doi.org/10.1016/j.chembiol.2015.04.005