Peripheral T cell lymphoma with a regulatory T cell phenotype: A Mexican case not associated with HTLV-1 virus infection

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Abstract

Peripheral T cell lymphomas are aggressive neoplasms with an overall bad prognosis. As occurred with B cell lymphomas, some T cell lymphomas have been correlated with a normal T cell counterpart. According to the actual WHO classification of tumors of hematopoietic and lymphoid tissues, the only T cell lymphoma characterized by a Treg phenotype is adult T cell leukemia/lymphoma (ATCLL), an entity defined by its etiologic association with HTLV-1 infection. We present a case of peripheral T cell lymphoma with a Treg phenotype not associated with HTLV-1 infection. We describe its pathological and clinical characteristics and discuss the presence of a Treg phenotype in T cell lymphomas. © 2014 Springer-Verlag Berlin Heidelberg.

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Llamas-Gutierrez, F., Espinoza-Macias, G., Neme-Yunes, Y., Aguilar-Guadarrama, R., Agreda-Vásquez, G., & Lome-Maldonado, C. (2014). Peripheral T cell lymphoma with a regulatory T cell phenotype: A Mexican case not associated with HTLV-1 virus infection. Journal of Hematopathology, 7(1), 39–45. https://doi.org/10.1007/s12308-014-0201-8

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