Cell therapy for cardiovascular disease: A comparison of methods of delivery

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Abstract

The field of myocardial regeneration utilizing novel cell-based therapies, gene transfer, and growth factors may prove to play an important role in the future management of ischemic heart disease and cardiomyopathy. Phases I and II clinical trials have been published for a variety of biologics utilizing four methods of delivery: systemic infusion, intracoronary infusion, transvenous coronary sinus, and intramyocardial. This review discusses the advantages and disadvantages of the delivery approaches above. © The Author(s) 2010.

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Dib, N., Khawaja, H., Varner, S., McCarthy, M., & Campbell, A. (2011). Cell therapy for cardiovascular disease: A comparison of methods of delivery. Journal of Cardiovascular Translational Research. Springer New York LLC. https://doi.org/10.1007/s12265-010-9253-z

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