Formation of a cytosolic ganglioside-protein complex following administration of photoreactive ganglioside GM1 to human fibroblasts in culture

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Abstract

A GM1 ganglioside derivative bearing a photoreactive nitrophenyl azide group and tritium labeled at the acetyl group of N-acetylneuraminic acid, has been administered to cultured human fibroblasts. With photolabeling experiments we found that a portion of the ganglioside in the cell cytosol was associated with a soluble protein of about 30 kDa. © 1990.

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Chigorno, V., Valsecchi, M., Acquotti, D., Sonnino, S., & Tettamanti, G. (1990). Formation of a cytosolic ganglioside-protein complex following administration of photoreactive ganglioside GM1 to human fibroblasts in culture. FEBS Letters, 263(2), 329–331. https://doi.org/10.1016/0014-5793(90)81406-E

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