Skip to main content

Nanotechnology-based drug delivery systems and herbal medicines: A review

201Citations
Citations of this article
422Readers
Mendeley users who have this article in their library.

Abstract

Herbal medicines have been widely used around the world since ancient times. The advancement of phytochemical and phytopharmacological sciences has enabled elucidation of the composition and biological activities of several medicinal plant products. The effectiveness of many species of medicinal plants depends on the supply of active compounds. Most of the biologically active constituents of extracts, such as flavonoids, tannins, and terpenoids, are highly soluble in water, but have low absorption, because they are unable to cross the lipid membranes of the cells, have excessively high molecular size, or are poorly absorbed, resulting in loss of bioavailability and efficacy. Some extracts are not used clinically because of these obstacles. It has been widely proposed to combine herbal medicine with nanotechnology, because nanostructured systems might be able to potentiate the action of plant extracts, reducing the required dose and side effects, and improving activity. Nanosystems can deliver the active constituent at a sufficient concentration during the entire treatment period, directing it to the desired site of action. Conventional treatments do not meet these requirements. The purpose of this study is to review nanotechnology-based drug delivery systems and herbal medicines. © 2014 Bonifácio et al.

Cite

CITATION STYLE

APA

Bonifácio, B. V., da Silva, P. B., Aparecido dos Santos Ramos, M., Maria Silveira Negri, K., Maria Bauab, T., & Chorilli, M. (2013, December 9). Nanotechnology-based drug delivery systems and herbal medicines: A review. International Journal of Nanomedicine. https://doi.org/10.2147/IJN.S52634

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free