Jiang et al. characterize primary Chinese triple-negative breast cancer (TNBC) and classify it into four subtypes. They find that these TNBCs have more frequent PIK3CA mutations and chromosome 22q11 copy-number gains than non-Asian TNBCs and that the LAR subtype has more ERBB2 somatic mutations and CDKN2A loss.
CITATION STYLE
Jiang, Y. Z., Ma, D., Suo, C., Shi, J., Xue, M., Hu, X., … Shao, Z. M. (2019). Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies. Cancer Cell, 35(3), 428-440.e5. https://doi.org/10.1016/j.ccell.2019.02.001
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