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Potential Benefit of Lymph Node Dissection During Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Systematic Review by the European Association of Urology Guidelines Panel on Non–muscle-invasive Bladder Cancer

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Abstract

Upper tract urothelial carcinoma (UTUC) represents an infrequent malignancy that carries a poor prognosis, with a high risk of lymphatic spread and subsequent disease progression. Template-based, complete lymph node dissection (LND) improves cancer-specific survival in patients with high-stage (≥pT2) UTUC and reduces the risk of local recurrence. LND improves survival in patients with high-stage disease of the renal pelvis if it is performed according to an anatomical template-based approach.

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Dominguez-Escrig, J. L., Peyronnet, B., Seisen, T., Bruins, H. M., Yuan, C. Y., Babjuk, M., … Rouprêt, M. (2019, March 1). Potential Benefit of Lymph Node Dissection During Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Systematic Review by the European Association of Urology Guidelines Panel on Non–muscle-invasive Bladder Cancer. European Urology Focus. Elsevier B.V. https://doi.org/10.1016/j.euf.2017.09.015

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