Adjuvant-enhanced mRNA vaccines

Citations of this article
Mendeley users who have this article in their library.
Get full text


Recent advances in molecular biology have led to dramatic enhancement of the stability of in vitro transcribed (IVT) messenger RNA (mRNA) and improvement in its translational efficacy. Nowadays, mRNA-based vaccines represent a promising approach in the field of anticancer immunotherapy, gaining attention over the earlier-established bacteria-, virus-, or cell-based vaccination approaches. Here, we present the experimental procedures employed in our laboratory to induce anticancer immune responses in different murine tumor models using IVT mRNA encoding for immune activation signals and antigens of interest.




Bialkowski, L., Van Der Jeught, K., Renmans, D., Van Weijnen, A., Heirman, C., Keyaerts, M., … Thielemans, K. (2017). Adjuvant-enhanced mRNA vaccines. In Methods in Molecular Biology (Vol. 1499, pp. 179–191). Humana Press Inc.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free