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Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Case presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.
Foster, D., Shaikh, M. F., Gleeson, E., Babcock, B. D., Lin, J., Ownbey, R. T., … Bowne, W. B. (2015). Pancreatic mucinous cystic neoplasm in a transgender patient. World Journal of Surgical Oncology, 13(1). https://doi.org/10.1186/s12957-015-0620-8