Pancreatic mucinous cystic neoplasm in a transgender patient

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Abstract

Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Case presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.

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Foster, D., Shaikh, M. F., Gleeson, E., Babcock, B. D., Lin, J., Ownbey, R. T., … Bowne, W. B. (2015). Pancreatic mucinous cystic neoplasm in a transgender patient. World Journal of Surgical Oncology, 13(1). https://doi.org/10.1186/s12957-015-0620-8

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