Effects of Yunnan Baiyao on blood coagulation parameters in beagles measured using kaolin activated thromboelastography and more traditional methods

1Citations
Citations of this article
8Readers
Mendeley users who have this article in their library.

Abstract

Yunnan Baiyao is anecdotally widely used in veterinary medicine for its pro-coagulation properties. There are no studies determining its effect on clotting tests. The purpose of this study was to determine the effect of oral Yunnan Baiyao (YB) on hemostasis by measuring coagulation via kaolin activated citrated whole blood thromboelastography (TEG), prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, and d-dimers. The study was a prospective, randomized controlled crossover trial. Eight healthy University of Calgary owned beagles were treated orally with either Yunnan Baiyao or placebo every 12 h for 5 treatments. Blood was collected immediately before treatment, 2 h after the last treatment, and 24 h after the last treatment. TEG analysis was run 30 ± 5 min after blood collection. All other coagulation analyses were sent to a reference laboratory for further analysis. No treatment adverse effects were observed. Oral YB increased R-time significantly within the YB group, but the increase was still within canine reference ranges. No other changes were observed. Oral YB at the dosage and frequency administered in this study did not produce any significant improvement in hemostatic parameters. There is a need for further research and scientific evidence for YB use and dosage.

Cite

CITATION STYLE

APA

Lee, A., Boysen, S. R., Sanderson, J., Wagg, C. R., & Chalhoub, S. (2017). Effects of Yunnan Baiyao on blood coagulation parameters in beagles measured using kaolin activated thromboelastography and more traditional methods. International Journal of Veterinary Science and Medicine, 5(1), 53–56. https://doi.org/10.1016/j.ijvsm.2017.01.004

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free