A systematic review of detailed neurological and psychiatric manifestations in patients with COVID-19

Abstract

Objectives: The aim of this research was to conduct a systematic review of studies examining neurological and psychiatric disorders in patients diagnosed with coronavirus 2019 (COVID-19). Methods: This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Me-ta-Analyses (PRISMA) recommendations. Related studies and case reports published in the ScienceDirect, PubMed, EMBASE, EBSCO, and Scopus databases between December 1, 2019 and September 1, 2020 were examined, and 21 studies that met the inclusion criteria were included in the review. The data gathered were summarized and analyzed. Results: All of the studies included were descriptive in nature. The most common findings were headache, central nervous system problems, cerebrovascular events, and polyneuropathy. Dizziness, Guillain-Barré syndrome, ischemic problems, and encephalopathy were among the other neuropsychiatric findings. Conclusion: Important psychiatric and neurological problems may begin with onset of COVID-19 and continue to have post-recovery effects. The results of this study indicated that neuropsychiatric signs and symptoms were common in COVID-19 patients and can prolong the recovery period. These data may raise awareness among clinicians and help them develop a care plan for neuropsychiatric problems in COVID-19 patients.