Antidiabetic activity with N-Hexane, ethyl-acetate and ethanol extract of halodule uninervis Seagrass

Abstract

The purpose of this research was to observe the antidiabetic activity from N-hexane, ethyl-acetate and ethanol extract of Halodule uninervis seagrass.The antidiabetic activity with extract concentrations of 125 ppm, 250 ppm, 500 ppm, 1000 ppm and 2000 ppm from seagrass extract with ethanol solvent showed that it had the ability as an anti-diabetic agent stronger than seagrass extract with n-hexane and ethyl acetate solvents. Calculation of IC50 of Halodule uninervis seagrass with ethanol extract was 74.99 ppm and ethyl acetate was 1,517,05 ppm. Glukobay as control was 0.27 ppm.