Multilevel Correlates of Same Day Poly-Product Use/Co-Use among Adolescents Who Use Tobacco and Cannabis

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Abstract

Introduction: Polysubstance use—use of more than one substance—is prevalent and an emergent public health issue. Yet not much is known about factors associated with same-day polysubstance use among adolescents. This study examined correlates of same-day tobacco and cannabis use/co-use among adolescents who use tobacco/cannabis. Methods: Cross-sectional data were from 10th and 11th grade students (n = 536) who reported tobacco/cannabis use. Regression models were used to examine intrapersonal, psychological (anxiety, depression), societal (societal concern, discrimination), and environmental (public and home secondhand smoke/vape exposure) correlates of past 30-day usage frequency (no, infrequent, and frequent use) of same-day: poly-product use (poly-tobacco/nicotine [use of different types of nicotine/tobacco]; poly-cannabis [use of different types of or marijuana/tetrahydrocannabinol (THC)]); poly-drug use [tobacco/nicotine and marijuana/THC], and nicotine and THC vape mixing. Results: Participants were predominantly Hispanic (66.23%) and male (62.50%). Among participants, 8.58%, reported frequent same-day polytobacco use, 13.81% frequent same-day poly-cannabis use, 13.25% frequent same-day poly-drug use, and 3.36% vape mixing. Past 30-day alcohol use was associated with higher odds (1.88–8.31, p

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Jacobs, W., Qin, W. A., Jafarzadeh, N. S., Barrington-Trimis, J., & Leventhal, A. M. (2026). Multilevel Correlates of Same Day Poly-Product Use/Co-Use among Adolescents Who Use Tobacco and Cannabis. Nicotine and Tobacco Research, 28(1), 26–35. https://doi.org/10.1093/ntr/ntaf150

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