MicroRNA: A new promising biomarker

Abstract

Understanding the molecular basis of life is at the center today, however, advances in the field of Molecular Biology and genomics improved the compassionate of the genetic basis of diseases in human. There is an increased interest in the function of non-coding RNA transcripts in early diagnosis and treatment to various diseases. MicroRNAs are classes of small non-coding RNAs that consist of 22-25 nucleotides, which are one of the most current forms of molecular characterization of tumours. The target MicroRNA regulates the mRNA translation that causes the subsequent decrease in the protein expression. This paper aims to review some of the accumulated literature that has proven that miRNAs are strong biomarkers in diagnosis and treatment of life threatening diseases such as cancer. © 2013 Rao VD.