First report of blaGES-1 in Proteus mirabilis clinical isolates

Abstract

Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting blaGES. The presence of these genes was determined using PCR and sequencing. We identified the presence of blaGES-1 in all three isolates. In addition, we identified the blaKPC-2 and blaNDM-1 genes in the two strains. These data emphasize the importance of monitoring and surveillance of all enterobacteria. The circulation of P. mirabilis strains carrying blaGES-1 constitutes a new scenario of resistance in this species and should be an epidemiological alert for global health.