Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorinated biphenyls (PCBs) in mice with a liver-specific deletion of cytochrome P450 reductase

Xueshu Li; Chunyun Zhang; Kai Wang; Hans Joachim Lehmler

Journal Article

Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorinated biphenyls (PCBs) in mice with a liver-specific deletion of cytochrome P450 reductase

Environmental Pollution (2020) 266

DOI: 10.1016/j.envpol.2020.115233

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Abstract

Mice with a liver-specific deletion of cytochrome P450 reductase display an altered congener-specific distribution of PCBs due to a fatty liver and impaired hepatic metabolism.

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Li, X., Zhang, C., Wang, K., & Lehmler, H. J. (2020). Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorinated biphenyls (PCBs) in mice with a liver-specific deletion of cytochrome P450 reductase. Environmental Pollution, 266. https://doi.org/10.1016/j.envpol.2020.115233

Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorinated biphenyls (PCBs) in mice with a liver-specific deletion of cytochrome P450 reductase

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