Insulin therapy of type 2 diabetes mellitus

Abstract

Basal insulin therapy in combination with oral hypoglycemic drugs has a special effect on fasting blood glucose. It is a simple way of introducing insulin therapy in patients with type 2 diabetes mellitus subjected to further prandial insulin therapy. Treatment with insulin mixtures reduces both fasting blood glucose and postprandial blood sugar, which has a negative effect on the development of vascular complications. With this simple therapy, there are limitations in everyday life and an adverse effect on the dynamics of body weight. Basal-bolus therapy focuses on pathophysiological changes, and with professional training and high-quality self-control provides good results with sufficient flexibility in everyday life. All insulin analogues have advantages over human insulins in terms of treatment outcomes, safety and patient compliance. All types of insulin therapy in clinical practice can be carried out by simple schemes.